Unfamiliar; not sympathomimetic; might maximize dopamine concentrations during the Mind by binding to your dopamine transporter and inhibiting dopamine reuptake

Langtidsbruk Leger som forskriver modafinil for en lengre periode, skal jevnlig revurdere langtidsbruk for den enkelte pasient ettersom effekten av modafinil ved langtidsbruk ikke har blitt studert (>9 uker). Spesielle pasientgrupper Nedsatt leverfunksjon: Ved alvorlig nedsatt leverfunksjon bør dosen halveres.

modafinil will lessen the level or outcome of levoketoconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified.

modafinil will boost the amount or outcome of diazepam buccal by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Observe. Solid or reasonable CYP2C19 inhibitors may possibly lower level of diazepam elimination, therefore raising adverse reactions to diazepam.

It's essential to Check out to make sure that it truly is safe so that you can choose modafinil with all your medicine and health problems. Tend not to get started, quit, or alter the dose of any drug without the need of checking with all your medical professional.

The US military has effectively utilized modafinil that can help helicopter pilots stay inform in the course of sustained functions.‍[9]

Nevertheless, concurrently, the fact that it really is in fact a strong drug that may have some serious Uncomfortable side effects, and also to which Absolutely everyone responds in different ways.

nefazodone will enhance the level or outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

modafinil will improve the amount or influence of mavacamten by affecting hepatic enzyme CYP2C19 metabolism. Contraindicated. Potent or reasonable CYP2C19 inhibitors may raise mavacamten systemic exposure, here causing heart failure due to systolic dysfunction.

modafinil will enhance the level or result of rabeprazole by impacting hepatic enzyme CYP2C19 metabolism. Minimal/Importance Unknown. Net effect on pantoprazole actions unidentified resulting from opposing consequences of CYP450 enzymes; observe

Clopidogrel efficacy might be minimized by medicines that inhibit CYP2C19. Inhibition of platelet aggregation by clopidogrel is solely on account of an active metabolite. Clopidogrel is metabolized to this Energetic metabolite partially by CYP2C19. .

Even though less widespread, the most significant Unintended effects of modafinil are described under, coupled with what to do when they come about.

istradefylline will increase the level or result of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

Change operate disorder, a affliction (largely in people Performing night, early early morning, or rotating shifts) involving problems sleeping when you need to and/or Excessive sleepiness when you have to be awake